![]() ![]() The regimen demonstrated the greatest effect against the pre-formed biofilm and the adhesion activity of S. The disinfecting regimen with the highest efficacy was the two-step system, first using multipurpose disinfecting solution containing edetate disodium and sorbic acid (MPDS+EDSA), followed by soaking in multipurpose solution (MPS). Staphylococcus aureus and Pseudomonas aeruginosa represented the highest biofilm producing bacteria on HEMA-based materials in this study. Results: Printed hydroxyethyl methacrylate (HEMA) CLs significantly demonstrated more biofilm staining and bacterial attachment when compared with non-printed HEMA CLs, while the Filcon II 3 and Nesofilcon A CLs possessed less biofilm biomass and adherent cells. Scanning electron microscopy (SEM) was performed for the morphological assessment of bacterial biofilm. Various CL disinfecting procedures were assessed for their efficacy to remove biofilm and reduce bacterial adhesion. Adhesion assay and standard plate count were carried out at time-interval periods within 24 h. Methods: Bacterial biofilm formation on CLs was evaluated by biomass assay. Then, the study was designed to investigate the effectiveness of various disinfecting solutions and evaluate the ability of cleaning regimens in terms of anti-bacterial adhesion and biofilm removal on different soft CL materials. Purpose: The present study aimed to compare the existing soft contact lens (CL) materials regarding their influence on bacterial biofilm formation and adhesion susceptibility. School of Medicine, Walailak University, Nakhon Si Thammarat, Thailand ![]() Auemphon Mordmuang, 1 Lunla Udomwech, 1, 2 Kulwadee Karnjana 1ġSchool of Medicine, Walailak University, Nakhon Si Thammarat, Thailand 2Walailak University Hospital, Walailak University, Nakhon Si Thammarat, Thailand ![]()
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